Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.49 |
| ▸ | CSNK1E | P49674 | 9/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 8/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 2/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27429471 | 0.96 | HRH4 (0.52) | HRH4CSNK1ECSNK1DPDE4APDE4B | |
| SCHEMBL27429480 | 0.92 | PDE4A (0.47) | HRH4CSNK1ECSNK1DPDE4APDE4B | |
| SCHEMBL27429475 | 0.88 | HRH4 (0.47) | HRH4CSNK1ECSNK1DPDE4APDE4B | |
| SCHEMBL27429472 | 0.86 | CSNK1E (0.45) | HRH4CSNK1ECSNK1DCCNE1CDK2 | |
| SCHEMBL27248344 | 0.79 | HRH4 (0.64) | HRH4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27248325 | 0.75 | HPGD (0.54) | HRH4HTR3A | |
| SCHEMBL27429713 | 0.75 | PTK2 (0.47) | HRH4CSNK1ECSNK1DPDE4APDE4B | |
| SCHEMBL27429799 | 0.74 | HRH4 (0.45) | HRH4CSNK1ECSNK1DPDE4APDE4B | |
| SCHEMBL27429801 | 0.73 | JAK3 (0.47) | HRH4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27432094 | 0.73 | HRH4 (0.45) | HRH4CSNK1ECSNK1DPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024118607-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | CHDI FOUNDATION, INC. (US) | 2024-06-06 | — | — | WO | disclosed |