SCHEMBL27432149

SCHEMBL27432149

CCCOc1ccc(Cl)c2c(=O)c3cc([SH]4c5ccccc5C(=O)c5cc(C(C)C)ccc54)ccc3sc12

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TNF P01375 1/20 0.31
RARA P10276 1/20 0.30
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30
RXRG P48443 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27432879 0.84
SCHEMBL27432150 0.81 TNF (0.32) TNF
SCHEMBL7769308 0.80 KDM4E (0.40) RARARXRARXRBRXRG
SCHEMBL27432010 0.78 KDM4E (0.34)
SCHEMBL27432148 0.76 NPC1 (0.31)
SCHEMBL27436212 0.74
SCHEMBL108341 0.73 MAPT (0.43)
SCHEMBL29428465 0.73 MAPT (0.43)
SCHEMBL29353913 0.73 MAPT (0.43)
SCHEMBL27432185 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024141537-A1 SULFONIUM SALT PHOTOINITIATORS AND METHODS OF LED CURING A COMPOSITION WITH SAID SULFONIUM SALT PHOTOINITIATORS ARKEMA FRANCE (FR) 2024-07-04 WO disclosed