Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.43 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27775192 | 1.00 | PPARA (0.54) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL27630621 | 0.94 | PPARA (0.49) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL27630618 | 0.88 | PPARA (0.46) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL11208077 | 0.86 | PPARA (0.56) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL27437587 | 0.86 | MAPT (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL1133621 | 0.86 | MAPT (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL27413116 | 0.86 | MAPT (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL27540285 | 0.86 | MAPT (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL27411658 | 0.86 | MAPT (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL27438257 | 0.86 | MAPT (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1105558-C | 2,2-dichloroalkane carboxylic acids, process for preparing the same, medicament containing the same and use for treating insulin resistance | ROCHE DIAGNOSTICS GMBH (DE) | 2003-04-16 | — | — | CN | disclosed |
| CN-1171050-A | 2, 2-Dichloroalkanecarboxylic acids, method for the production thereof, medicaments containing the same and use thereof for the treatment of insulin resistance | BOEHRINGER MANNHEIM GMBH (DE) | 1998-01-21 | — | — | CN | disclosed |