SCHEMBL27434

SCHEMBL27434

CC(C)(CC1C(O)[C@@H](CO)O[C@H]1n1ccc(=O)[nH]c1=O)[Si](C)(C)O

nearest known ligand 0.64

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.64
SLC28A2 O43868 1/20 0.64
SLC29A1 Q99808 1/20 0.64
SLC28A3 Q9HAS3 1/20 0.64
P2RY2 P41231 7/20 0.47
P2RY14 Q15391 8/20 0.45
P2RY6 Q15077 7/20 0.45
P2RY4 P51582 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14615954 0.92 SLC28A1 (0.52) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL13120307 0.92 SLC28A1 (0.52) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL9946958 0.84 SLC28A1 (0.80) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL9945538 0.84 SLC28A1 (0.80) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL17547236 0.83 P2RY2 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL14615827 0.83 P2RY2 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL18464354 0.83 SLC28A1 (0.74) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL18465153 0.83 SLC28A1 (0.74) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL19750923 0.82 TK2 (0.51)
SCHEMBL13120067 0.82 P2RY14 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012024776-A1 BLOCK SYNTHESIS OF OLIGORIBONUCLEOTIDES THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) 2012-03-01 WO disclosed