Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 2/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 11/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 11/20 | 0.36 |
| ▸ | SRC | P12931 | 4/20 | 0.36 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27411925 | 0.87 | SRC (0.33) | DDB1CRBNSRCKDM5A | |
| SCHEMBL27434692 | 0.85 | CRBN (0.47) | DDB1CRBNIKZF3ALDH1A1CHRM2 | |
| SCHEMBL19709588 | 0.72 | PSEN1 (0.36) | PSEN1PSEN2KCNH2APH1BNCSTN | |
| SCHEMBL22511869 | 0.69 | CRBN (0.35) | DDB1CRBNIKZF3ALDH1A1CHRM2 | |
| SCHEMBL23798041 | 0.69 | CRBN (0.42) | DDB1CRBNIKZF3ALDH1A1CHRM2 | |
| SCHEMBL25091816 | 0.68 | CRBN (0.44) | DDB1CRBNIKZF3ALDH1A1CHRM2 | |
| SCHEMBL22711433 | 0.66 | CRBN (0.42) | PSEN1PSEN2KCNH2APH1BNCSTN | |
| SCHEMBL20436926 | 0.66 | DDB1 (0.35) | DDB1CRBN | |
| SCHEMBL20812705 | 0.65 | CRBN (0.54) | PSEN1PSEN2KCNH2APH1BNCSTN | |
| SCHEMBL26158796 | 0.65 | CRBN (0.45) | DDB1CRBNIKZF3ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112119-A1 | DEGRADER FOR DECOMPOSING CMET PROTEIN, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 이노큐어테라퓨틱스 | 2024-05-30 | — | — | WO | disclosed |