Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.60 |
| ▸ | KDR | P35968 | 3/20 | 0.60 |
| ▸ | BRAF | P15056 | 1/20 | 0.58 |
| ▸ | PKMYT1 | Q99640 | 17/20 | 0.50 |
| ▸ | WEE1 | P30291 | 3/20 | 0.48 |
| ▸ | MYT1 | Q01538 | 2/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27434703 | 0.89 | SRC (0.53) | SRCKDRBRAFPKMYT1WEE1 | |
| SCHEMBL27435615 | 0.87 | SRC (0.53) | SRCKDRBRAFPKMYT1WEE1 | |
| SCHEMBL27435283 | 0.87 | PKMYT1 (0.47) | SRCKDRBRAFPKMYT1WEE1 | |
| SCHEMBL27435297 | 0.85 | PKMYT1 (0.46) | SRCKDRBRAFPKMYT1WEE1 | |
| SCHEMBL27435614 | 0.85 | SRC (0.46) | SRCKDRBRAFPKMYT1WEE1 | |
| SCHEMBL27435289 | 0.84 | PKMYT1 (0.49) | SRCKDRBRAFPKMYT1WEE1 | |
| SCHEMBL27435712 | 0.83 | PKMYT1 (0.46) | SRCKDRPKMYT1WEE1MYT1 | |
| SCHEMBL27434850 | 0.82 | PKMYT1 (0.47) | SRCKDRPKMYT1WEE1MYT1 | |
| SCHEMBL27435703 | 0.81 | PKMYT1 (0.49) | SRCKDRBRAFPKMYT1WEE1 | |
| SCHEMBL27435608 | 0.81 | PKMYT1 (0.51) | PKMYT1WEE1MYT1CDK1CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024138109-A2 | PHENYL-PYRAZOLE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |