Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27705656 | 0.90 | TSHR (0.39) | CES1THRBMEN1HTTKMT2A | |
| SCHEMBL8414742 | 0.86 | CES1 (0.44) | CES1THRBMEN1HTTKMT2A | |
| SCHEMBL28752982 | 0.86 | TSHR (0.36) | CES1TSHRHCAR2 | |
| SCHEMBL27638107 | 0.84 | CES1 (0.42) | CES1THRBMEN1HTTKMT2A | |
| SCHEMBL11323980 | 0.81 | CES1 (0.39) | CES1THRBMEN1HTTKMT2A | |
| SCHEMBL30634500 | 0.80 | CES1 (0.47) | CES1THRBMEN1HTTKMT2A | |
| SCHEMBL27608939 | 0.79 | HCAR2 (0.30) | HCAR2 | |
| SCHEMBL29112564 | 0.79 | MEN1 (0.45) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL8769729 | 0.78 | CES1 (0.45) | CES1THRBMEN1HTTKMT2A | |
| SCHEMBL28813963 | 0.78 | TSHR (0.40) | THRBMEN1HTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1105799-A | Carbostyril derivatives as matrix metalloproteinases inhibitors | OTSUKA PHARMA CO LTD (JP) | 1995-07-26 | — | — | CN | disclosed |