⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27440322 | 0.67 | — | — | |
| SCHEMBL688735 | 0.66 | — | — | |
| SCHEMBL8588629 | 0.65 | — | — | |
| SCHEMBL4618642 | 0.65 | — | — | |
| Ammonia Solution, Strong SCHEMBL27615334 | 0.65 | — | — | |
| SCHEMBL8588628 | 0.63 | — | — | |
| SCHEMBL27296968 | 0.63 | — | — | |
| SCHEMBL9079795 | 0.60 | — | — | |
| SCHEMBL25256547 | 0.59 | — | — | |
| SCHEMBL17425150 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1192739-A | N-heteroaryl-pyridinesulfonamide derivatives and their use as endothelin antagonists | ZENECA LTD (GB) | 1998-09-09 | — | — | CN | claimed |
| CN-1137519-A | Substituted benzenesulfonylureas and -thioureas, processes for their preparation, their use for production of pharmaceutical preparations, and pharmaceutical preparations containing them | HOECHST AG (DE) | 1996-12-11 | — | — | CN | disclosed |