SCHEMBL274428

SCHEMBL274428

c1ccc(C2COCCO2)cc1

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.67
ADRA2A P08913 5/20 0.42
CHRM2 P08172 3/20 0.42
CHRM4 P08173 3/20 0.42
CHRM1 P11229 3/20 0.42
CHRM3 P20309 3/20 0.42
CHRM5 P08912 2/20 0.41
MEN1 O00255 1/20 0.38
CYP2C19 P33261 1/20 0.38
KMT2A Q03164 1/20 0.38
ADRA1A P35348 3/20 0.37
SLC6A2 P23975 2/20 0.36
SLC6A3 Q01959 2/20 0.36
SLC6A4 P31645 1/20 0.36
HTR2B P41595 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL27508099 0.98 TSHR (0.64) TSHRADRA2ACHRM2CHRM4CHRM1
Hydrochloric Acid SCHEMBL28154420 0.96 TSHR (0.61) TSHRADRA2ACHRM2CHRM4CHRM1
Oxirane SCHEMBL1524760 0.89 TSHR (0.85) TSHRADRA2ACHRM2CHRM4CHRM1
Hexane SCHEMBL28169135 0.88 TSHR (0.52) TSHRADRA2ACHRM2CHRM4CHRM1
Toluene SCHEMBL28217011 0.88 TSHR (0.52) TSHRADRA2ACHRM2CHRM4CHRM1
SCHEMBL15145195 0.84 CHRM2 (0.52) TSHRCHRM2CHRM3CHRM5
Fluoride SCHEMBL28066844 0.84 TSHR (0.94) TSHRADRA2ACHRM2CHRM4CHRM1
SCHEMBL1943997 0.81
SCHEMBL21026 0.81
SCHEMBL28467238 0.81 TSHR (1.00) TSHRADRA2ACHRM2CHRM4CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2705 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250186415-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2025-06-12 US claimed
EP-4489858-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS Harrow IP, LLC (US) 2025-01-15 EP claimed
EP-3805824-B1 IDENTIFICATION MEDIUM, AND METHOD FOR DETERMINING AUTHENTICITY OF IDENTIFICATION MEDIUM ZEON CORP (JP) 2024-10-09 EP claimed
US-11814563-B2 Bioreachable chiral dopants for liquid crystal applications ZYMERGEN INC. (US) 2023-11-14 US claimed
WO-2023172240-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS HARROW IP, LLC (US) 2023-09-14 WO claimed
US-20230203378-A1 FORMULATIONS OF BIOREACHABLE DOPANTS FOR LIQUID CRYSTALS KENT STATE UNIVERSITY 2023-06-29 US claimed
EP-3611760-B1 COMPOSITES WITH ENHANCED THERMAL CONDUCTIVITY AND METHOD PREPARING THE SAME KOREA INST SCI & TECH (KR) 2022-10-05 EP claimed
US-20220025267-A1 BIOREACHABLE CHIRAL DOPANTS FOR LIQUID CRYSTAL APPLICATIONS ZYMERGEN ACQUISITION SUB, INC. 2022-01-27 US claimed
EP-3891252-A2 BIOREACHABLE CHIRAL DOPANTS FOR LIQUID CRYSTAL APPLICATIONS Zymergen Inc. (US) 2021-10-13 EP claimed
CN-113454187-A Biologically available chiral dopants for liquid crystal applications 齐默尔根公司 2021-09-28 CN claimed
US-5043093-A Liquid crystals MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-08-27 US claimed
WO-1991009026-A2 PHENYLDIOXANES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-06-27 WO claimed
US-4992434-A Prevention of infestation of plants by phytopathogenic microorganisms CIBA-GEIGY CORPORATION (US) 1991-02-12 US claimed
US-4948796-A TREATING CEREBO-VASCULARE DISEASES TOYAMA CHEMICAL CO., LTD. (JP) 1990-08-14 US claimed
US-4733949-A LOW TEMPERATURE RESPONSE TIME HITACHI, LTD. (JP) 1988-03-29 US claimed
US-4659499-A Liquid crystal materials CRYSTALOID ELECTRONICS COMPANY (US) 1987-04-21 US claimed
EP-0128006-A2 A soil-disease-controlling agent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-12-12 EP claimed
US-4413145-A Process for the synthesis of 3-keto-cyclopentene-5-oxy derivatives having insecticide activity CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1983-11-01 US claimed
US-4364838-A Liquid crystal mixtures HOFFMANN-LA ROCHE INC. (US) 1982-12-21 US claimed
US-4180646-A BIOERODABLE SUSTAINED RELEASE COTAINGS ALZA CORPORATION (US) 1979-12-25 US claimed