SCHEMBL2744461

C=CC(=O)O[Si](CC(C)C)(CC(C)C)O[Si](O[Si](C)(C)C)(O[Si](C(C)C)(C(C)C)C(C)C)O[Si](C(C)C)(C(C)C)C(C)C

nearest known ligand 0.36

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	TSHR	P16473	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2744435	0.93	TSHR (0.41)	TSHR
SCHEMBL2743702	0.87	TSHR (0.37)	TSHR
SCHEMBL2743862	0.87	TSHR (0.43)	TSHR
SCHEMBL2744262	0.85	TSHR (0.44)	TSHR
SCHEMBL2744393	0.85	TSHR (0.35)	TSHR
SCHEMBL2744226	0.84	TSHR (0.39)	TSHR
SCHEMBL2744265	0.83	TSHR (0.36)	TSHR
SCHEMBL2744049	0.81	TSHR (0.32)	TSHR
SCHEMBL2744665	0.81	TSHR (0.41)	TSHR
SCHEMBL2744586	0.81	TSHR (0.41)	TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8178710-B2	Silyl (meth)acrylate compound containing a siloxy group having a bulky substituent and its production method	SHIN-ETSU CHEMICAL CO., LTD. (JP)	2012-05-15	—	—	US	disclosed
EP-2182000-A1	Silyl (meth)acrylate compound containing a siloxy group having a bulky substituent and its production method	Shin-Etsu Chemical Co., Ltd. (JP)	2010-05-05	—	—	EP	disclosed
US-20100105938-A1	SILYL (METH)ACRYLATE COMPOUND CONTAINING A SILOXY GROUP HAVING A BULKY SUBSTITUENT AND ITS PRODUCTION METHOD	SHIN-ETSU CHEMICAL CO., LTD. (JP)	2010-04-29	—	—	US	disclosed