SCHEMBL27445375

SCHEMBL27445375

c1ccc(-c2ccc(-c3cccc(-n4c5ccccc5c5ccc6oc7c(-c8nc(-c9ccc(-c%10ccccc%10)cc9)nc(-c9ccc(-c%10ccccc%10)cc9)n8)cccc7c6c54)c3)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.34
HPSE Q9Y251 2/20 0.33
PIM1 P11309 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
PIM3 Q86V86 1/20 0.32
PIM2 Q9P1W9 1/20 0.32
MAPK14 Q16539 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PGR P06401 1/20 0.30
PIK3CD O00329 1/20 0.30
PIK3CA P42336 1/20 0.30
PIK3CB P42338 1/20 0.30
PIK3CG P48736 1/20 0.30
PRKDC P78527 1/20 0.30
MAPT P10636 1/20 0.30
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27445379 1.00 PDE10A (0.34) PDE10AHPSEPIM1CSNK2A2CSNK2B
SCHEMBL27445366 1.00 PDE10A (0.34) PDE10AHPSEPIM1CSNK2A2CSNK2B
SCHEMBL27445355 1.00 PDE10A (0.34) PDE10AHPSEPIM1CSNK2A2CSNK2B
SCHEMBL27445370 1.00 PDE10A (0.34) PDE10AHPSEPIM1CSNK2A2CSNK2B
SCHEMBL27445363 0.99 PDE10A (0.34) PDE10AHPSEPIM1CSNK2A2CSNK2B
SCHEMBL27445372 0.98 HPSE (0.33) PDE10AHPSEPIM1CSNK2A2CSNK2B
SCHEMBL27445374 0.98 HPSE (0.33) PDE10AHPSEPIM1CSNK2A2CSNK2B
SCHEMBL27445356 0.98 HPSE (0.33) PDE10AHPSEPIM1CSNK2A2CSNK2B
SCHEMBL27445433 0.97 PDE10A (0.32) PDE10AHPSEPIM1CSNK2A2CSNK2B
SCHEMBL27445377 0.97 HPSE (0.34) PDE10AHPSEPIM1CSNK2A2CSNK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030894-B2 Composition for organic optoelectronic device, organic optoelectronic device and display device SAMSUNG SDI CO., LTD. (KR) 2024-07-09 US disclosed
US-12030894-B2 Composition for organic optoelectronic device, organic optoelectronic device and display device SAMSUNG SDI CO., LTD. (KR) 2024-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12030894-B2 Composition for organic optoelectronic device, organic optoelectronic device and display device OR10J3, OCIAD2, OCIAD1 PDE10A 1752/4885HPSE 3724/4885PIM1 2606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.