Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9232127 | 0.85 | KDM4E (0.54) | KDM4EHSD17B10F2ALDH1A1CYP1A2 | |
| SCHEMBL27948878 | 0.81 | KDM4E (0.67) | KDM4EHSD17B10F2ALDH1A1CYP1A2 | |
| SCHEMBL28309356 | 0.81 | KDM4E (0.52) | KDM4EHSD17B10F2ALDH1A1CYP1A2 | |
| SCHEMBL5721982 | 0.80 | KDM4E (0.55) | KDM4EHSD17B10F2ALDH1A1CYP1A2 | |
| SCHEMBL3218684 | 0.77 | PARP10 (0.50) | KDM4EHSD17B10F2ALDH1A1CYP1A2 | |
| SCHEMBL31664571 | 0.76 | TNKS2 (0.61) | KDM4EALDH1A1CYP1A2CYP2C19TNKS2 | |
| SCHEMBL2799080 | 0.76 | TNKS2 (0.61) | KDM4EALDH1A1CYP1A2CYP2C19TNKS2 | |
| SCHEMBL9029582 | 0.76 | CYP1A2 (0.56) | KDM4EHSD17B10F2ALDH1A1CYP1A2 | |
| SCHEMBL31343793 | 0.75 | KDM4E (0.64) | KDM4EHSD17B10ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL14829872 | 0.75 | KDM4E (0.64) | KDM4EHSD17B10ALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1118456-C | 1,2-dihydro-2-oxoquinoline derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2003-08-20 | — | — | CN | disclosed |
| CN-1280569-A | 1, 2-dihydro-2-oxoquinoline derivative | TAISHO PHARMACEUTICAL CO LTD (JP) | 2001-01-17 | — | — | CN | disclosed |