⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1988711 | 1.00 | — | — | |
| SCHEMBL9069778 | 0.81 | — | — | |
| SCHEMBL2744870 | 0.81 | — | — | |
| SCHEMBL29030244 | 0.80 | CYP2D6 (0.50) | — | |
| SCHEMBL52133 | 0.78 | — | — | |
| SCHEMBL756717 | 0.78 | — | — | |
| SCHEMBL690785 | 0.76 | — | — | |
| SCHEMBL10806356 | 0.76 | — | — | |
| SCHEMBL10402740 | 0.76 | — | — | |
| SCHEMBL10821242 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2183273-B1 | CYCLIC DEPSIPEPTIDES | NOVARTIS AG (CH) | 2017-04-05 | — | — | EP | claimed |
| US-9127044-B2 | Cyclic depsipeptides | NOVARTIS AG (CH) | 2015-09-08 | — | — | US | claimed |
| US-20120196790-A1 | CYCLIC DEPSIPEPTIDES | NOVARTIS AG (CH) | 2012-08-02 | — | — | US | claimed |
| US-8178650-B2 | Cyclic depsipeptides | NOVARTIS AG (CH) | 2012-05-15 | — | — | US | claimed |
| EP-2183273-A1 | CYCLIC DEPSIPEPTIDES | Novartis Ag (CH) | 2010-05-12 | — | — | EP | claimed |
| US-20090156472-A1 | Cyclic Depsipeptides | NOVARTIS AG (CH) | 2009-06-18 | — | — | US | claimed |
| WO-2009024527-A1 | CYCLIC DEPSIPEPTIDES | NOVARTIS AG (CH) | 2009-02-26 | — | — | WO | claimed |
| EP-2183273-B1 | CYCLIC DEPSIPEPTIDES | NOVARTIS AG (CH) | 2017-04-05 | — | — | EP | disclosed |
| US-9127044-B2 | Cyclic depsipeptides | NOVARTIS AG (CH) | 2015-09-08 | — | — | US | disclosed |
| US-20120196790-A1 | CYCLIC DEPSIPEPTIDES | NOVARTIS AG (CH) | 2012-08-02 | — | — | US | disclosed |
| US-8178650-B2 | Cyclic depsipeptides | NOVARTIS AG (CH) | 2012-05-15 | — | — | US | disclosed |
| EP-2183273-A1 | CYCLIC DEPSIPEPTIDES | Novartis Ag (CH) | 2010-05-12 | — | — | EP | disclosed |
| US-20090156472-A1 | Cyclic Depsipeptides | NOVARTIS AG (CH) | 2009-06-18 | — | — | US | disclosed |
| WO-2009024527-A1 | CYCLIC DEPSIPEPTIDES | NOVARTIS AG (CH) | 2009-02-26 | — | — | WO | disclosed |