SCHEMBL2744715

SCHEMBL2744715

C=CC(=O)O[Si](O[Si](C)(C)O[Si](CC)(CC)CC)(C(C)C)C(C)C

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2743688 0.91 TSHR (0.39) TSHRHPGD
SCHEMBL2744525 0.88 TSHR (0.33) TSHR
SCHEMBL2744742 0.84 TSHR (0.33) TSHRHPGD
SCHEMBL2744204 0.84 TSHR (0.33) TSHRHPGD
SCHEMBL2743969 0.84 TSHR (0.35) TSHRHPGD
SCHEMBL2744042 0.83 TSHR (0.34) TSHR
SCHEMBL2743764 0.81 TSHR (0.38) TSHRHPGD
SCHEMBL2744046 0.80 TSHR (0.36) TSHR
SCHEMBL2743847 0.79 TSHR (0.38) TSHRHPGD
SCHEMBL2744835 0.78 TSHR (0.37) TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178710-B2 Silyl (meth)acrylate compound containing a siloxy group having a bulky substituent and its production method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-05-15 US disclosed
EP-2182000-A1 Silyl (meth)acrylate compound containing a siloxy group having a bulky substituent and its production method Shin-Etsu Chemical Co., Ltd. (JP) 2010-05-05 EP disclosed
US-20100105938-A1 SILYL (METH)ACRYLATE COMPOUND CONTAINING A SILOXY GROUP HAVING A BULKY SUBSTITUENT AND ITS PRODUCTION METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-04-29 US disclosed