Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 9/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.38 |
| ▸ | CHRNG | P07510 | 2/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.38 |
| ▸ | CHRND | Q07001 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 3/20 | 0.36 |
| ▸ | NPY4R | P50391 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22138596 | 1.00 | FURIN (0.39) | FURINCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL20705515 | 1.00 | FURIN (0.39) | FURINCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL15699736 | 0.94 | FURIN (0.40) | FURINCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL25787504 | 0.94 | FURIN (0.40) | FURINCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL30297062 | 0.93 | HTT (0.41) | FURINCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL22138594 | 0.93 | FURIN (0.39) | FURINCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL19681567 | 0.93 | FURIN (0.39) | FURINCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL24296990 | 0.93 | FURIN (0.40) | FURINCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL23429029 | 0.92 | HTT (0.41) | FURINCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL24864407 | 0.92 | FURIN (0.39) | FURINHTTNPY1RNPY4RROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024138000-A1 | PRODRUGS OF TOPOISOMERASE I INHIBITOR FOR ADC CONJUGATIONS AND METHODS OF USE THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |