Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.62 |
| ▸ | CES1 | P23141 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL240086 | 0.88 | GSK3B (0.71) | GSK3BCES1CA1CA2TDP1 | |
| SCHEMBL9734470 | 0.85 | GSK3B (0.67) | GSK3BCES1CA1CA2TDP1 | |
| SCHEMBL8024787 | 0.85 | GSK3B (0.67) | GSK3BCES1CA1CA2TDP1 | |
| SCHEMBL11705103 | 0.83 | GSK3B (0.65) | GSK3BCES1CA1CA2TDP1 | |
| SCHEMBL6650467 | 0.81 | GSK3B (0.62) | GSK3BCES1CA1CA2TDP1 | |
| SCHEMBL9439988 | 0.81 | GSK3B (0.62) | GSK3BCES1CA1CA2TDP1 | |
| SCHEMBL10789142 | 0.81 | GSK3B (0.62) | GSK3BCES1CA1CA2TDP1 | |
| SCHEMBL18045554 | 0.81 | GSK3B (0.73) | GSK3BCES1CA1CA2TDP1 | |
| SCHEMBL18045560 | 0.81 | GSK3B (0.62) | GSK3BCES1CA1CA2TDP1 | |
| SCHEMBL4477185 | 0.81 | CES1 (0.70) | GSK3BCES1CA1CA2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1040876-C | New derivatives of erythromycin, their preparation process, their use as medicaments | ROUSSEL UCLAF (FR) | 1998-11-25 | — | — | CN | disclosed |
| CN-1090581-A | The preparation method of the novel derivative of erythromycin and they and as the application of medicine | ROUSSEL UCLAF (FR) | 1994-08-10 | — | — | CN | disclosed |