Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12191508 | 0.80 | — | — | |
| SCHEMBL2345052 | 0.80 | — | — | |
| SCHEMBL12191506 | 0.80 | — | — | |
| SCHEMBL8316116 | 0.78 | CYP1A2 (0.31) | CYP1A2 | |
| SCHEMBL27477336 | 0.76 | CYP1A2 (0.33) | CYP1A2KDM4EKMT2A | |
| SCHEMBL14961820 | 0.75 | — | — | |
| SCHEMBL5983613 | 0.75 | — | — | |
| SCHEMBL14961821 | 0.75 | — | — | |
| SCHEMBL12437872 | 0.75 | — | — | |
| SCHEMBL23334387 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1058394-A | Piperidines of new replacement and preparation method thereof and as the purposes of inhibitors of cholesterol synthesis | MERRELL DOW PHARMA (US) | 1992-02-05 | — | — | CN | disclosed |