Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469558 | 0.80 | PDE10A (0.47) | PDE10ANPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL24590442 | 0.79 | PDE10A (0.43) | PDE10ANPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL11791999 | 0.77 | KDM4E (0.43) | PDE10ANPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL6835105 | 0.74 | PDE10A (0.39) | PDE10ANPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL24289437 | 0.73 | PDE10A (0.47) | PDE10ANPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL9963715 | 0.71 | PDE10A (0.46) | PDE10ANPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL30020271 | 0.71 | PPARG (0.45) | PDE10ANPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL30020312 | 0.71 | PPARG (0.45) | PDE10ANPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL30020938 | 0.71 | PPARG (0.45) | PDE10ANPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL28320480 | 0.71 | SMN1; SMN2 (0.46) | PDE10ANPC1RAB9AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1071912-A | Dicyclo [7,3,1] 13 carbon-4-alkene-2,6-dialkyne and method for making thereof | BRISTOL MYERS SQUIBB CO (US) | 1993-05-12 | — | — | CN | disclosed |