SCHEMBL27447516

SCHEMBL27447516

CCCCN(C(=S)S)c1ccccc1.[Cu]

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.49
JAK2 O60674 1/20 0.49
RAB9A P51151 1/20 0.49
PAX8 Q06710 1/20 0.49
TP53 P04637 2/20 0.45
ESR1 P03372 1/20 0.43
ALDH1A1 P00352 3/20 0.43
MAPT P10636 2/20 0.43
GAA P10253 2/20 0.43
ADRB2 P07550 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
ALOX12 P18054 1/20 0.43
CRHBP P24387 1/20 0.43
HTT P42858 1/20 0.43
CRHR2 Q13324 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
GLA P06280 1/20 0.42
TSHR P16473 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1286183 0.98 NPC1 (0.50) NPC1JAK2RAB9APAX8TP53
SCHEMBL29002331 0.97 NPC1 (0.49) NPC1JAK2RAB9APAX8TP53
SCHEMBL27930529 0.95 NPC1 (0.55) NPC1JAK2RAB9APAX8TP53
SCHEMBL27382712 0.93 NPC1 (0.57) NPC1JAK2RAB9APAX8TP53
SCHEMBL1286067 0.93 NPC1 (0.56) NPC1JAK2RAB9APAX8TP53
SCHEMBL1286223 0.92 NPC1 (0.59) NPC1JAK2RAB9APAX8TP53
SCHEMBL10618320 0.92 NPC1 (0.59) NPC1JAK2RAB9APAX8TP53
SCHEMBL27939770 0.92 NPC1 (0.59) NPC1JAK2RAB9APAX8TP53
SCHEMBL27261905 0.90 NPC1 (0.57) NPC1JAK2RAB9APAX8TP53
SCHEMBL27930530 0.89 TP53 (0.47) NPC1JAK2RAB9APAX8TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103237782-B Method for inhibiting unwanted free-radical polymerization of acrylic acid present in liquid phase P BASF SE (DE) 2016-01-13 CN disclosed
CN-103237782-A Method for inhibiting unwanted free-radical polymerization of acrylic acid present in liquid phase P BASF SE 2013-08-07 CN disclosed
CN-101679199-B Method for distilling liquid containing easily polymerizable compound NIPPON CATALYTIC CHEM IND 2013-05-29 CN disclosed
CN-1472187-B Method for producing acrylic acid NIPPON CATALYTIC CHEM IND 2010-12-15 CN disclosed
CN-101679199-A Method for distilling liquid containing easily polymerizable compound NIPPON CATALYTIC CHEM IND 2010-03-24 CN disclosed
CN-100516006-C Method for producing easily polymerizable substance NIPPON CATALYTIC CHEM IND (JP) 2009-07-22 CN disclosed
CN-100341841-C Method for producing acrylic acid NIPPON CATALYTIC CHEM IND (JP) 2007-10-10 CN disclosed
CN-1250510-C Process for decomposing Michael type adduct NIPPON CATALYTIC CHEM IND (JP) 2006-04-12 CN disclosed
CN-1217911-C Method for preventing easily polymerizable substance from polymerization and method for producing acrylic acid or ester thereof NIPPON CATALYTIC CHEM IND (JP) 2005-09-07 CN disclosed
CN-1550480-A Method for producing easily polymerizable substance 株式会社日本触媒 2004-12-01 CN disclosed
CN-1480441-A Process for producing acroleic acid ��ʽ�����ձ���ý 2004-03-10 CN disclosed
CN-1480442-A Method for producing acrylic acid ��ʽ�����ձ���ý 2004-03-10 CN disclosed
CN-1472187-A Method for producing acrylic acid ��ʽ�����ձ���ý 2004-02-04 CN disclosed
CN-1453260-A Process for decomposing Michael type adduct NIPPON CATALYTIC CHEM IND (JP) 2003-11-05 CN disclosed
CN-1389448-A Method for preventing easily polymerizable substance from polymerizing and method for producing acrylic acid or ester thereof NIPPON CATALYTIC CHEM IND (JP) 2003-01-08 CN disclosed
CN-1083410-C Method for inhibiting polymerization of vinyl compounds IDEMITSU PETROCHEMICAL CO (JP) 2002-04-24 CN disclosed
CN-1069305-C Method of inhibiting vinyl compound polymerization IDEMITSU PETROCHEMICAL CO (JP) 2001-08-08 CN disclosed
CN-1198730-A Method for inhibiting polymerization of vinyl compounds IDEMITSU PETROCHEMICAL CO (JP) 1998-11-11 CN disclosed
CN-1157606-A Method of inhibiting vinyl compound polymerization IDEMITSU PETROCHEMICAL CO (JP) 1997-08-20 CN disclosed