Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2743677 | 0.92 | TSHR (0.35) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL2744536 | 0.92 | TSHR (0.35) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL2744082 | 0.92 | TSHR (0.35) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL2744886 | 0.87 | TSHR (0.32) | TSHRHPGD | |
| SCHEMBL2744709 | 0.86 | TSHR (0.31) | TSHRHPGD | |
| SCHEMBL2744126 | 0.86 | TSHR (0.31) | TSHRHPGD | |
| SCHEMBL2744199 | 0.86 | TSHR (0.31) | TSHRHPGD | |
| SCHEMBL2744835 | 0.85 | TSHR (0.37) | TSHRHPGD | |
| SCHEMBL2744793 | 0.85 | TSHR (0.37) | TSHRHPGD | |
| SCHEMBL2744276 | 0.84 | TSHR (0.34) | TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2182000-B1 | Silyl (meth)acrylate compound containing a siloxy group having a bulky substituent and its production method | SHINETSU CHEMICAL CO (JP) | 2013-06-12 | — | — | EP | disclosed |
| US-8178710-B2 | Silyl (meth)acrylate compound containing a siloxy group having a bulky substituent and its production method | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| EP-2182000-A1 | Silyl (meth)acrylate compound containing a siloxy group having a bulky substituent and its production method | Shin-Etsu Chemical Co., Ltd. (JP) | 2010-05-05 | — | — | EP | disclosed |
| US-20100105938-A1 | SILYL (METH)ACRYLATE COMPOUND CONTAINING A SILOXY GROUP HAVING A BULKY SUBSTITUENT AND ITS PRODUCTION METHOD | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-04-29 | — | — | US | disclosed |