Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 6/20 | 0.44 |
| ▸ | CTSK | P43235 | 5/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12056576 | 1.00 | PPARG (0.51) | PPARGPPARAKLK5CTSSCTSK | |
| SCHEMBL9922080 | 1.00 | PPARG (0.51) | PPARGPPARAKLK5CTSSCTSK | |
| SCHEMBL6747610 | 0.84 | KLK5 (0.49) | KLK5CA1CA2CA7ATM | |
| SCHEMBL7471521 | 0.84 | KLK5 (0.49) | PPARGPPARAKLK5CTSSCTSK | |
| SCHEMBL7471500 | 0.84 | KLK5 (0.49) | PPARGPPARAKLK5CTSSCTSK | |
| SCHEMBL6747612 | 0.84 | KLK5 (0.49) | KLK5CA1CA2CA7ATM | |
| SCHEMBL7471507 | 0.84 | KLK5 (0.49) | PPARGPPARAKLK5CTSSCTSK | |
| SCHEMBL27486450 | 0.84 | KLK5 (0.63) | KLK5CTSSCTSKATMPSEN1 | |
| SCHEMBL8486327 | 0.84 | KLK5 (0.63) | KLK5CTSSCTSKATMPSEN1 | |
| SCHEMBL27796636 | 0.84 | KLK5 (0.63) | KLK5CTSSCTSKATMPSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1112125-A | Acyloxyhexanoic acid derivatives | CIBA GEIGY AG (CH) | 1995-11-22 | — | — | CN | disclosed |