SCHEMBL27449231

SCHEMBL27449231

CC1=Cc2c(-c3ccc(Cl)cc3)cccc2C1[Zr](C)(C)(=[SiH2])C1C(C)=Cc2c(-c3ccc(Cl)cc3)cccc21

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.32
HTR1A P08908 2/20 0.31
HTR7 P34969 2/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7648704 0.89 EDNRB (0.31)
Hydrochloric Acid SCHEMBL5952381 0.87 EDNRB (0.30)
SCHEMBL2561824 0.87 PDCD1 (0.33)
SCHEMBL27427511 0.86 ESR2 (0.36) HTR1AHTR7MEN1NPC1CYP1A2
SCHEMBL27451098 0.86 PLK4 (0.31)
SCHEMBL27480317 0.86 HTR2C (0.33) PTGS2HTR1AHTR7SLC6A4SLC6A3
Fluoride SCHEMBL7638687 0.86 PDCD1 (0.32)
Hydrochloric Acid SCHEMBL271771 0.86 PDCD1 (0.32)
Hydrochloric Acid SCHEMBL6436500 0.86 PDCD1 (0.32)
SCHEMBL27427510 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1116852-A Propylene elastomer MITSUI PETROCHEMICAL IND (JP) 1996-02-14 CN disclosed