SCHEMBL2745181

SCHEMBL2745181

CC/C=C\C/C=C\C/C=C\C/C=C\CC/C=C/C=C/C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 3/20 1.00
CNR1 P21554 1/20 0.56
CNR2 P34972 1/20 0.56
ALDH1A1 P00352 6/20 0.55
OXER1 Q8TDS5 6/20 0.55
CYP19A1 P11511 4/20 0.55
PPARG P37231 3/20 0.55
MAPT P10636 3/20 0.55
RXRA P19793 2/20 0.55
FFAR1 O14842 2/20 0.55
PTGS1 P23219 4/20 0.52
F7 P08709 3/20 0.52
F3 P13726 3/20 0.52
KMT2A Q03164 2/20 0.52
PPARD Q03181 2/20 0.52
ADORA3 P0DMS8 1/20 0.52
KDM4E B2RXH2 1/20 0.49
MEN1 O00255 1/20 0.49
NR1I2 O75469 1/20 0.49
LMNA P02545 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2745188 1.00 PPARA (1.00) PPARACNR1CNR2ALDH1A1OXER1
SCHEMBL6405870 0.98 PPARA (0.96) PPARACNR1CNR2ALDH1A1OXER1
SCHEMBL5886676 0.98 PPARA (0.96) PPARACNR1CNR2ALDH1A1OXER1
SCHEMBL2744282 0.98 PPARA (0.96) PPARACNR1CNR2ALDH1A1OXER1
SCHEMBL4445473 0.94 PPARA (0.89) PPARACNR1CNR2ALDH1A1OXER1
SCHEMBL4445477 0.94 PPARA (0.89) PPARACNR1CNR2ALDH1A1OXER1
SCHEMBL13674213 0.94 PPARA (0.89) PPARACNR1CNR2ALDH1A1OXER1
SCHEMBL18274958 0.93 PPARA (0.86) PPARACNR1CNR2ALDH1A1OXER1
SCHEMBL18274959 0.93 PPARA (0.86) PPARACNR1CNR2ALDH1A1OXER1
SCHEMBL18010751 0.93 PPARA (0.86) PPARACNR1CNR2ALDH1A1OXER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120232143-A1 LIPID DERIVATIVES PRONOVA BIOPHARMA NORGE AS 2012-09-13 US disclosed
US-20120232143-A1 LIPID DERIVATIVES PRONOVA BIOPHARMA NORGE AS 2012-09-13 US disclosed
US-20120232143-A1 LIPID DERIVATIVES PRONOVA BIOPHARMA NORGE AS 2012-09-13 US disclosed
US-8178708-B2 Lipid derivatives PRONOVA BIOPHARMA NORGE AS (NO) 2012-05-15 US disclosed
US-8178708-B2 Lipid derivatives PRONOVA BIOPHARMA NORGE AS (NO) 2012-05-15 US disclosed
US-8178708-B2 Lipid derivatives PRONOVA BIOPHARMA NORGE AS (NO) 2012-05-15 US disclosed
US-20090105499-A1 LIPID DERIVATIVES PRONOVA BIOPHARMA NORGE AS (NO) 2009-04-23 US disclosed
US-20090105499-A1 LIPID DERIVATIVES PRONOVA BIOPHARMA NORGE AS (NO) 2009-04-23 US disclosed
US-20090105499-A1 LIPID DERIVATIVES PRONOVA BIOPHARMA NORGE AS (NO) 2009-04-23 US disclosed
WO-2007107869-A2 LIPID DERIVATIVES PRONOVA BIOPHARMA NORGE AS (NO) 2007-09-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120232143-A1 LIPID DERIVATIVES CYP4F3, STARD3, PLIN3 PPARA 802/4885CNR1 184/4885CNR2 217/4885
US-20090105499-A1 LIPID DERIVATIVES PLIN3, STARD3, CYP4F3 PPARA 885/4885CNR1 230/4885CNR2 196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.