Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 16/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCNK | O75909 | 1/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | CDK14 | O94921 | 1/20 | 0.33 |
| ▸ | CCNY | Q8ND76 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30950490 | 1.00 | BTK (0.44) | BTKLCKKDM4EMAPTKMT2A | |
| SCHEMBL27452106 | 0.93 | BTK (0.53) | BTKLCKEGFR | |
| SCHEMBL30950447 | 0.93 | BTK (0.53) | BTKLCKEGFR | |
| SCHEMBL27452109 | 0.92 | BTK (0.43) | BTKLCKCCNKCDK12EGFR | |
| SCHEMBL30950579 | 0.92 | BTK (0.43) | BTKLCKCCNKCDK12EGFR | |
| SCHEMBL30950488 | 0.90 | BTK (0.47) | BTKLCKKDM4EMAPTKMT2A | |
| SCHEMBL27453493 | 0.90 | BTK (0.47) | BTKLCKKDM4EMAPTKMT2A | |
| SCHEMBL27461700 | 0.85 | BTK (0.54) | BTKLCK | |
| SCHEMBL27454577 | 0.84 | BTK (0.43) | BTKLCKCCNKCDK12EGFR | |
| SCHEMBL30950455 | 0.83 | BTK (0.50) | BTKLCKKDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129395-A1 | BTK INHIBITORS | GWYNANT THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |