Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.53 |
| ▸ | LCK | P06239 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | CD69 | Q07108 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27452619 | 1.00 | BTK (0.53) | BTKLCKKCNH2CD69CYP3A4 | |
| SCHEMBL27459174 | 0.93 | BTK (0.48) | BTKLCKKCNH2CD69CYP3A4 | |
| SCHEMBL27452454 | 0.92 | BTK (0.53) | BTKLCKKCNH2CYP2C9 | |
| SCHEMBL27452456 | 0.92 | BTK (0.53) | BTKLCKKCNH2CYP2C9 | |
| SCHEMBL27452241 | 0.85 | BTK (0.68) | BTKLCKKCNH2 | |
| SCHEMBL27452458 | 0.81 | BTK (0.67) | BTKLCKKCNH2 | |
| SCHEMBL17660318 | 0.80 | BTK (0.80) | BTKLCKKCNH2CD69CYP3A4 | |
| SCHEMBL17645895 | 0.79 | BTK (0.81) | BTKLCK | |
| SCHEMBL17645727 | 0.79 | BTK (0.78) | BTKLCKKCNH2CD69CYP3A4 | |
| SCHEMBL30950600 | 0.78 | BTK (0.68) | BTKLCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129395-A1 | BTK INHIBITORS | GWYNANT THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |