SCHEMBL27453

SCHEMBL27453

[CH2]c1ccccc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zinc Chloride SCHEMBL28846764 0.91 TSHR (0.47)
SCHEMBL2090588 0.77 CYP2A6 (0.50)
SCHEMBL96975 0.75
SCHEMBL647360 0.75
1,2-Dichlorobenzene SCHEMBL5190 0.73
1,2-Dichlorobenzene SCHEMBL1155123 0.73 TSHR (1.00)
1,2-Dichlorobenzene SCHEMBL10593125 0.73
1,2-Dichlorobenzene SCHEMBL29350623 0.73
SCHEMBL58138 0.73
1,4-Dichlorobenzene SCHEMBL1155125 0.72 TSHR (0.77)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 18525 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399206-A1 PAPD5 AND/OR PAPD7 INHIBITING 4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID DERIVATIVES Redona Therapeutics, Inc. (US) 2024-07-17 EP claimed
EP-4399212-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-07-17 EP claimed
CN-118307495-A Synthesis method of 2-phenylbenzyl-2-dimethylamine-1- (4-morpholinyl benzyl) butanone 甘肃得中聚成新材料有限公司 2024-07-09 CN claimed
WO-2024133200-A1 P2X3 RECEPTOR ANTAGONISTS RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA SPA (IT) 2024-06-27 WO claimed
CN-118239883-A Preparation method of lysine-specific demethylase 1 (LSD 1) inhibitor 江苏联环药业股份有限公司 2024-06-25 CN claimed
CN-118206748-A PCB electroplating additive and preparation method thereof 广东利尔化学有限公司 2024-06-18 CN claimed
CN-118206439-A Continuous production method of o (p) chlorobenzaldehyde 山东道可化学有限公司 2024-06-18 CN claimed
CN-118201914-A 4-Oxo-1, 4-dihydroquinoline-3-carboxylic acid derivatives as PAPD5 and/or PAPD7 inhibitors 雷多纳治疗公司 2024-06-14 CN claimed
CN-118159542-A Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents 拜耳公司 2024-06-07 CN claimed
CN-114456038-B Synthesis method of para-substituted chlorobenzyl compound 拓松(绍兴)生物医药科技有限公司 2024-05-28 CN claimed
US-3971804-A ACARICIDES, FUNGICIDES, INSECTICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US claimed
US-3963429-A Coloring of organic materials with asymmetric thioindigoid compounds MITSUI TOATSU CHEMICALS, INCORPORATED (JA) 1976-06-15 US claimed
US-3963714-A Quaternary ammonium salts BASF AKTIENGESELLSCHAFT (DT) 1976-06-15 US claimed
US-3960831-A WET FASTNESS, COLORFASTNESS BAYER AKTIENGESELLSCHAFT (DT) 1976-06-01 US claimed
US-3956374-A Aryl-oxo-heptenoic acids MERCK & CO., INC. (US) 1976-05-11 US claimed
US-3950408-A Process for preparing [1-oxo-2-cyclopentyl (or 2-isopropyl)-2-methyl-6,7-dichloro-5-indanyloxy] acetic acid MERCK & CO., INC. (US) 1976-04-13 US claimed
US-3950347-A NAPHTHOLACTAM DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-04-13 US claimed
US-3948903-A Substituted N-(1,2-dihydro-2-oxonicotinyl)-cephalexins and -cephaloglycins PARKE, DAVIS & COMPANY (US) 1976-04-06 US claimed
US-3947470-A CORONARY VASODILATORS, TREATMENT OF ANGINA PECTORIS SMITHKLINE CORPORATION (US) 1976-03-30 US claimed
US-3930671-A Color former and pressure-sensitive copying paper FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US claimed