SCHEMBL27453370

SCHEMBL27453370

N#Cc1cccc(-c2cccc(-c3nc(-c4ccccc4)nc(-c4cccc(-c5ccccc5-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)c4)n3)c2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 8/20 0.53
CYP3A4 P08684 7/20 0.53
CLK4 Q9HAZ1 5/20 0.53
LMNA P02545 5/20 0.53
CYP2D6 P10635 5/20 0.53
MEN1 O00255 4/20 0.53
ALDH1A1 P00352 4/20 0.53
KMT2A Q03164 4/20 0.53
CYP2C19 P33261 4/20 0.53
HSD17B10 Q99714 3/20 0.53
TSHR P16473 3/20 0.53
CYP2C9 P11712 2/20 0.53
MAPK1 P28482 2/20 0.50
TP53 P04637 2/20 0.49
KDM4E B2RXH2 1/20 0.49
MAPT P10636 1/20 0.49
ADORA2A P29274 3/20 0.47
ADORA1 P30542 2/20 0.47
ADORA3 P0DMS8 1/20 0.47
GABRG2 P18507 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27453707 1.00 CYP1A2 (0.53) CYP1A2CYP3A4CLK4LMNACYP2D6
SCHEMBL27453375 1.00 CYP1A2 (0.53) CYP1A2CYP3A4CLK4LMNACYP2D6
SCHEMBL27453711 0.99 CYP1A2 (0.52) CYP1A2CYP3A4CLK4LMNACYP2D6
SCHEMBL27453713 0.97 CYP1A2 (0.51) CYP1A2CYP3A4CLK4LMNACYP2D6
SCHEMBL27453614 0.96 CYP1A2 (0.52) CYP1A2CYP3A4CLK4LMNACYP2D6
SCHEMBL27453367 0.96 CYP1A2 (0.52) CYP1A2CYP3A4CLK4LMNACYP2D6
SCHEMBL27453360 0.96 CYP1A2 (0.52) CYP1A2CYP3A4CLK4LMNACYP2D6
SCHEMBL27453380 0.95 CYP1A2 (0.54) CYP1A2CYP3A4CLK4LMNACYP2D6
SCHEMBL27453488 0.95 CYP1A2 (0.54) CYP1A2CYP3A4CLK4LMNACYP2D6
SCHEMBL27453597 0.95 MEN1 (0.49) CYP1A2CYP3A4CLK4LMNACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024112021-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2024-05-30 WO disclosed