Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 11/20 | 0.46 |
| ▸ | IKZF3 | Q9UKT9 | 5/20 | 0.46 |
| ▸ | TNF | P01375 | 2/20 | 0.46 |
| ▸ | IL1B | P01584 | 2/20 | 0.46 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26930449 | 0.89 | CRBN (0.46) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL26930466 | 0.88 | CRBN (0.48) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL26930503 | 0.88 | CRBN (0.48) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL30659363 | 0.88 | CRBN (0.48) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL31542343 | 0.86 | CRBN (0.46) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL30659445 | 0.85 | CRBN (0.46) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL30659404 | 0.85 | CRBN (0.46) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL26930523 | 0.85 | CRBN (0.43) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL27454823 | 0.85 | CRBN (0.43) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL26930520 | 0.85 | CRBN (0.46) | CRBNDDB1IKZF3TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4539849-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 Therapeutics, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| US-20250121070-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 THERAPEUTICS, INC. (US) | 2025-04-17 | — | — | US | disclosed |
| WO-2023244764-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |
| WO-2023244764-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250121070-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | SMARCA2, SMARCE1, SMARCA1 | CRBN 29/4885DDB1 320/4885IKZF3 664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.