Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13791152 | 0.81 | HTR2A (0.43) | HTR2AHTR2CMAPTRAB9AKMT2A | |
| SCHEMBL515180 | 0.80 | IDO1 (0.53) | MAPTALDH1A1L3MBTL1IDO1TAAR1 | |
| SCHEMBL18994627 | 0.79 | CYP1A2 (0.51) | HTR2AHTR2CKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL8926 | 0.79 | TAAR1 (0.52) | HTR2AHTR2CMAPTALDH1A1L3MBTL1 | |
| SCHEMBL172225 | 0.79 | HTR2A (0.46) | HTR2AHTR2CMAPTL3MBTL1IDO1 | |
| SCHEMBL29792655 | 0.79 | TAAR1 (0.52) | HTR2AHTR2CMAPTALDH1A1L3MBTL1 | |
| SCHEMBL3906398 | 0.78 | HTR2A (0.41) | HTR2AHTR2CKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL10870949 | 0.78 | IDO1 (0.43) | HTR2AMAPTRAB9AALDH1A1L3MBTL1 | |
| Bromide SCHEMBL15741709 | 0.77 | TAAR1 (0.50) | HTR2AHTR2CMAPTALDH1A1L3MBTL1 | |
| SCHEMBL422832 | 0.77 | HTR2A (0.44) | HTR2AHTR2CMAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12029739-B2 | SHP2 inhibitor and use thereof | KANAPH THERAPEUTICS INC. (KR) | 2024-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12029739-B2 | SHP2 inhibitor and use thereof | PTPN1, PTPN5, PTPN2 | HTR2A 4330/4885HTR2C 4638/4885MAPT 3027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.