Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | DAO | P14920 | 1/20 | 0.65 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.61 |
| ▸ | CES2 | O00748 | 2/20 | 0.61 |
| ▸ | CES1 | P23141 | 2/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL10413125 | 1.00 | TSHR (0.65) | TSHRDAONAPRTTP53SRD5A2 | |
| Benzenethiol SCHEMBL3155034 | 0.97 | TSHR (0.62) | TSHRDAONAPRTTP53SRD5A2 | |
| Benzoic Acid SCHEMBL20568103 | 0.95 | TSHR (0.74) | TSHRDAONAPRTTP53SRD5A2 | |
| Benzene SCHEMBL28112975 | 0.92 | TSHR (0.67) | TSHRDAONAPRTTP53SRD5A2 | |
| SCHEMBL40593 | 0.89 | TSHR (0.71) | TSHRDAONAPRTTP53SRD5A2 | |
| SCHEMBL6513037 | 0.86 | TSHR (0.67) | TSHRDAONAPRTTP53SRD5A2 | |
| SCHEMBL31427160 | 0.86 | TSHR (0.67) | TSHRDAONAPRTTP53SRD5A2 | |
| SCHEMBL5511182 | 0.86 | TSHR (0.67) | TSHRDAONAPRTTP53SRD5A2 | |
| SCHEMBL6519285 | 0.86 | TSHR (0.67) | TSHRDAONAPRTTP53SRD5A2 | |
| Methane SCHEMBL28305326 | 0.86 | TSHR (0.67) | TSHRDAONAPRTTP53SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1113846-C | Process for producing terephthalic acid | SUNKYONG IND LTD (KR) | 2003-07-09 | — | — | CN | disclosed |