Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 11/20 | 0.64 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.64 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.45 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.45 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9495760 | 1.00 | LPAR3 (0.64) | LPAR3LPAR2LPAR1CYP3A4P2RY10 | |
| SCHEMBL2563554 | 1.00 | LPAR3 (0.64) | LPAR3LPAR2LPAR1CYP3A4P2RY10 | |
| SCHEMBL9011421 | 1.00 | LPAR3 (0.64) | LPAR3LPAR2LPAR1CYP3A4P2RY10 | |
| SCHEMBL1115770 | 1.00 | LPAR3 (0.64) | LPAR3LPAR2LPAR1CYP3A4P2RY10 | |
| SCHEMBL9497660 | 1.00 | LPAR3 (0.64) | LPAR3LPAR2LPAR1CYP3A4P2RY10 | |
| SCHEMBL4072457 | 1.00 | LPAR3 (0.64) | LPAR3LPAR2LPAR1CYP3A4P2RY10 | |
| SCHEMBL27759601 | 1.00 | LPAR3 (0.64) | LPAR3LPAR2LPAR1CYP3A4P2RY10 | |
| SCHEMBL1537958 | 0.98 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4P2RY10 | |
| SCHEMBL9499739 | 0.92 | CYP3A4 (0.54) | LPAR3LPAR2LPAR1CYP3A4P2RY10 | |
| SCHEMBL3463162 | 0.87 | LPAR3 (0.75) | LPAR3LPAR2LPAR1CYP3A4P2RY10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1121389-C | Cyanoguanidine as cell proliferation inhibitor | LEO PHARM PROD LTD (DK) | 2003-09-17 | — | — | CN | disclosed |
| CN-1258277-A | Cyanoguanidines as cell proliferation inhibitors | LEO PHARM PROD LTD (DK) | 2000-06-28 | — | — | CN | disclosed |