Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL283399 | 0.83 | FFAR3 (0.50) | FFAR3LCKFYNALDH1A1TSHR | |
| SCHEMBL122036 | 0.82 | — | — | |
| Acetic Acid SCHEMBL7862250 | 0.80 | FFAR3 (0.47) | FFAR3LCKFYNALDH1A1TSHR | |
| Tert-Butanol SCHEMBL6273948 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL11060692 | 0.78 | — | — | |
| Tert-Butanol SCHEMBL28003770 | 0.74 | FFAR3 (0.58) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetic Acid SCHEMBL29127390 | 0.74 | FFAR3 (0.58) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetic Acid SCHEMBL28764933 | 0.72 | — | — | |
| Bicarbonate SCHEMBL28549988 | 0.72 | TSHR (0.41) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetic Acid SCHEMBL28597052 | 0.70 | FFAR3 (0.64) | FFAR3LCKFYNALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100572561-C | One pipe method half-nest type PCR detection reagent and detection method of Vibrio vulnificus | UNIV HAINAN (CN) | 2009-12-23 | — | — | CN | claimed |
| CN-100557026-C | The test kit of rapid detection vibrio proteolyticus and detection method thereof | UNIV JINAN (CN) | 2009-11-04 | — | — | CN | claimed |
| CN-100543147-C | Accurately identify the test kit and the authentication method thereof of Nian and southern catfish | UNIV SOUTHWEST (CN) | 2009-09-23 | — | — | CN | claimed |
| CN-100487134-C | Reagent kit and detection method for quickly detecting shark vibrio | UNIV JINAN (CN) | 2009-05-13 | — | — | CN | claimed |
| CN-101200756-A | Reagent kit for rapid detection of vibrio harveyi and detection method thereof | UNIV GUANGDONG OCEAN (CN) | 2008-06-18 | — | — | CN | claimed |
| CN-101200757-A | Rapid detection reagent kit for human great pathogen-comma bacillus and detection method thereof | UNIV GUANGDONG OCEAN (CN) | 2008-06-18 | — | — | CN | claimed |
| CN-101024858-A | Reagent box for accurately discriminating catfish and large-mouth catfish and discrimination method | XINAN UNIV (CN) | 2007-08-29 | — | — | CN | claimed |
| CN-1995372-A | Reagent kit and detection method for quickly detecting shark vibrio | UNIV JINAN (CN) | 2007-07-11 | — | — | CN | claimed |
| CN-1974785-A | Reagent kit for fast detection of vibrio proteolyticus and its detection process | UNIV JINAN (CN) | 2007-06-06 | — | — | CN | claimed |
| CN-1232653-C | Kit for fast test of vibrio harveyi and the test method thereof | SOUTH CHINA SEA INST OCEANOLOG (CN) | 2005-12-21 | — | — | CN | claimed |
| CN-1232654-C | Reagent kit for quick test of vibrio vulnificus and the test method thereof | SOUTH CHINA SEA INST OCEANOLOG (CN) | 2005-12-21 | — | — | CN | claimed |
| CN-1166783-C | Reagent kit and process for quickly detecting schwann's bacterial of alga | 中国科学院南海海洋研究所 | 2004-09-15 | — | — | CN | claimed |
| CN-1527057-A | Reagent kit for quick test of vibrio vulnificus and the test method thereof | 中国科学院南海海洋研究所 | 2004-09-08 | — | — | CN | claimed |
| CN-1527056-A | Kit for fast test of vibrio harveyi and the test method thereof | 中国科学院南海海洋研究所 | 2004-09-08 | — | — | CN | claimed |
| CN-1142291-C | Reagent kit and method for quickly detecting alga-dissolving vibrio | 中国科学院南海海洋研究所 | 2004-03-17 | — | — | CN | claimed |
| CN-1373358-A | Reagent kit and method for quickly detecting alga-dissolving vibrio | NANHAI INST OF OCEANOLOGY CHIN (CN) | 2002-10-09 | — | — | CN | claimed |
| CN-1363685-A | Reagent kit and process for quickly detecting schwann's bacterial of alga | NANHAI INST OF OCEANOLOGY CHIN (CN) | 2002-08-14 | — | — | CN | claimed |
| CN-100572561-C | One pipe method half-nest type PCR detection reagent and detection method of Vibrio vulnificus | UNIV HAINAN (CN) | 2009-12-23 | — | — | CN | disclosed |
| CN-1995372-A | Reagent kit and detection method for quickly detecting shark vibrio | UNIV JINAN (CN) | 2007-07-11 | — | — | CN | disclosed |
| CN-1974785-A | Reagent kit for fast detection of vibrio proteolyticus and its detection process | UNIV JINAN (CN) | 2007-06-06 | — | — | CN | disclosed |