Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.59 |
| ▸ | NOS2 | P35228 | 6/20 | 0.55 |
| ▸ | ARG2 | P78540 | 4/20 | 0.53 |
| ▸ | ARG1 | P05089 | 3/20 | 0.53 |
| ▸ | NOS1 | P29475 | 4/20 | 0.52 |
| ▸ | NOS3 | P29474 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25660446 | 0.93 | GSR (0.56) | GSRNOS2ARG2ARG1NOS1 | |
| SCHEMBL31348916 | 0.86 | GSR (0.76) | GSRNOS2ARG2ARG1NOS1 | |
| SCHEMBL8894128 | 0.86 | GSR (0.76) | GSRNOS2ARG2ARG1NOS1 | |
| SCHEMBL8893420 | 0.86 | GSR (0.76) | GSRNOS2ARG2ARG1NOS1 | |
| SCHEMBL4848672 | 0.86 | GSR (0.76) | GSRNOS2ARG2ARG1NOS1 | |
| SCHEMBL9829771 | 0.86 | GSR (0.76) | GSRNOS2ARG2ARG1NOS1 | |
| SCHEMBL6741106 | 0.86 | GSR (0.76) | GSRNOS2ARG2ARG1NOS1 | |
| SCHEMBL5743303 | 0.84 | GSR (0.61) | GSRNOS2ARG2ARG1NOS1 | |
| SCHEMBL5653470 | 0.84 | GSR (0.61) | GSRNOS2ARG2ARG1NOS1 | |
| SCHEMBL25660589 | 0.84 | GSR (0.61) | GSRNOS2ARG2ARG1NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1122600-A | Inhibitors of second messenger cell signaling | CELL THERAPEUTICS INC (US) | 1996-05-15 | — | — | CN | disclosed |