Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.60 |
| ▸ | LCK | P06239 | 2/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | FGR | P09769 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | SRC | P12931 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30950577 | 1.00 | BTK (0.60) | BTKLCKAURKAFGRCYP2C9 | |
| SCHEMBL27452243 | 0.93 | BTK (0.53) | BTKLCKAURKAFGRCYP2C9 | |
| SCHEMBL30950604 | 0.93 | BTK (0.53) | BTKLCKAURKAFGRCYP2C9 | |
| SCHEMBL27458797 | 0.92 | BTK (0.54) | BTKLCKAURKAFGRCYP2C9 | |
| SCHEMBL30950581 | 0.92 | BTK (0.54) | BTKLCKAURKAFGRCYP2C9 | |
| SCHEMBL30950532 | 0.91 | BTK (0.52) | BTKLCKAURKAFGRCYP2C9 | |
| SCHEMBL27458798 | 0.91 | BTK (0.52) | BTKLCKAURKAFGRCYP2C9 | |
| SCHEMBL27452171 | 0.91 | BTK (0.52) | BTKLCKAURKAFGRCYP2C9 | |
| SCHEMBL27458795 | 0.91 | BTK (0.49) | BTKLCKAURKAFGRCYP2C9 | |
| SCHEMBL27431093 | 0.86 | BTK (0.59) | BTKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129395-A1 | BTK INHIBITORS | GWYNANT THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |