SCHEMBL27459262

SCHEMBL27459262

Cn1nc(-c2c(F)cc(Cl)c3nc(N)sc23)c(Cl)c1C[SH](=O)=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27474320 0.89
SCHEMBL6592617 0.80 SMN1; SMN2 (0.37) SMN1; SMN2ALDH1A1
SCHEMBL6592854 0.79 SMN1; SMN2 (0.35) SMN1; SMN2ALDH1A1
SCHEMBL6586722 0.76 SMN1; SMN2 (0.34) SMN1; SMN2ALDH1A1
SCHEMBL27475595 0.74
SCHEMBL7508191 0.71 SMN1; SMN2 (0.33) SMN1; SMN2ALDH1A1
SCHEMBL6587324 0.68 MEN1 (0.30)
SCHEMBL6589551 0.67 SMN1; SMN2 (0.35) SMN1; SMN2ALDH1A1
SCHEMBL6591420 0.67
SCHEMBL6588028 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1145626-C Substituted pyrazole-3-yl benzazoles �����ɷ� 2004-04-14 CN disclosed