Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.77 |
| ▸ | PI4KA | P42356 | 3/20 | 0.68 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.68 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.68 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.68 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.68 |
| ▸ | ADCY5 | O95622 | 11/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | AHCY | P23526 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28984637 | 0.88 | ADORA2A (1.00) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL4351091 | 0.84 | ADORA2A (0.75) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL30315880 | 0.84 | ADORA2A (0.75) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL987094 | 0.84 | ADORA2A (0.75) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL5188585 | 0.84 | ADORA2A (0.75) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL12321001 | 0.84 | ADORA2A (0.75) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL8173417 | 0.82 | ADORA2A (0.71) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL978424 | 0.81 | ADORA2A (1.00) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL21435666 | 0.81 | ADORA2A (1.00) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL10474172 | 0.81 | ADCY5 (0.74) | ADORA2API4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1125946-A | Novel carbocyclic nucleoside agents useful as selective inhibitors of proinflammatory cytokines | MERRELL DOW PHARMA (US) | 1996-07-03 | — | — | CN | disclosed |