Acrylamide

Acrylamide

SCHEMBL27459596

C=CC(N)=O.CC(=CC=Cc1ccccc1)C(=O)O

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.48
AKR1C3 P42330 1/20 0.47
GRIK1 P39086 1/20 0.44
GAA P10253 1/20 0.44
GLA P06280 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CYP2C19 P33261 1/20 0.41
LMNA P02545 4/20 0.40
CYP3A4 P08684 1/20 0.40
PTGS1 P23219 1/20 0.40
MAOB P27338 1/20 0.39
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 1/20 0.39
HDAC3 O15379 2/20 0.39
HDAC4 P56524 2/20 0.39
HDAC1 Q13547 2/20 0.39
HDAC7 Q8WUI4 2/20 0.39
HDAC2 Q92769 2/20 0.39
HDAC10 Q969S8 2/20 0.39
HDAC11 Q96DB2 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL448096 0.90 AKR1C3 (0.50) MCL1AKR1C3GRIK1GAAGLA
Butadiene SCHEMBL9678114 0.89 AKR1C3 (0.52) MCL1AKR1C3GRIK1GAAGLA
SCHEMBL693055 0.88 AKR1C3 (0.59) MCL1AKR1C3GRIK1GAAGLA
SCHEMBL16462 0.88 AKR1C3 (0.59) MCL1AKR1C3GRIK1GAAGLA
SCHEMBL10454886 0.88 AKR1C3 (0.59) MCL1AKR1C3GRIK1GAAGLA
Styrene SCHEMBL451196 0.87 AKR1C3 (0.50) MCL1AKR1C3GRIK1GAAGLA
Methacrylic Acid SCHEMBL5875032 0.85 AKR1C3 (0.52) MCL1AKR1C3GRIK1GAAGLA
SCHEMBL28318920 0.85 AKR1C3 (0.52) MCL1AKR1C3GRIK1GAAGLA
Acrylonitrile SCHEMBL1275059 0.83 MCL1 (0.50) MCL1AKR1C3GRIK1GAAGLA
SCHEMBL11056779 0.82 GAA (0.50) MCL1AKR1C3GRIK1GAAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1140668-C Composite thickening agent for printing with reactive dye 沈阳化工研究院 2004-03-03 CN disclosed
CN-1261116-A Composite thickening agent for printing with reactive dye SHENYANG GENERAL INST OF CHEMI (CN) 2000-07-26 CN disclosed