Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.46 |
| ▸ | LCK | P06239 | 2/20 | 0.46 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27454436 | 0.91 | BTK (0.49) | BTKLCKKCNH2 | |
| SCHEMBL27460368 | 0.89 | BTK (0.46) | BTKLCKKCNH2 | |
| SCHEMBL27454641 | 0.88 | BTK (0.45) | BTKLCKCCNKCDK12 | |
| SCHEMBL27454230 | 0.87 | BTK (0.46) | BTKLCKKCNH2 | |
| SCHEMBL30950556 | 0.87 | BTK (0.46) | BTKLCKKCNH2 | |
| SCHEMBL27454433 | 0.86 | BTK (0.48) | BTKLCKKCNH2 | |
| SCHEMBL27454577 | 0.86 | BTK (0.43) | BTKLCKCCNKCDK12 | |
| SCHEMBL27452692 | 0.85 | BTK (0.51) | BTKLCKKCNH2 | |
| SCHEMBL27460369 | 0.85 | BTK (0.49) | BTKLCKKCNH2 | |
| SCHEMBL30950447 | 0.81 | BTK (0.53) | BTKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129395-A1 | BTK INHIBITORS | GWYNANT THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |