Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23969941 | 0.79 | HRH3 (0.35) | HRH3CHRM2CHRM1HTR1AADRA2A | |
| SCHEMBL3975015 | 0.70 | HRH3 (0.38) | HRH3CHRM2CHRM1HTR1AADRA2A | |
| SCHEMBL188685 | 0.67 | HRH3 (0.65) | HRH3SMN1; SMN2KDM4EMAOAMAOB | |
| SCHEMBL20043816 | 0.64 | HRH3 (0.51) | HRH3CYP2D6SMN1; SMN2MAOAMAOB | |
| SCHEMBL4491187 | 0.64 | HRH3 (0.44) | HRH3DRD1OPRM1SMN1; SMN2KDM4E | |
| SCHEMBL933180 | 0.64 | HRH3 (0.38) | HRH3CHRM2CHRM1HTR1AADRA2A | |
| SCHEMBL19764133 | 0.63 | HRH3 (0.44) | HRH3CHRM2CHRM1SMN1; SMN2CHRM4 | |
| SCHEMBL16712916 | 0.63 | HRH3 (0.59) | HRH3SMN1; SMN2MAOAMAOBSCN1A | |
| SCHEMBL16513840 | 0.62 | HRH3 (0.50) | HRH3SMN1; SMN2MAOAMAOB | |
| SCHEMBL3022887 | 0.62 | HRH3 (0.43) | HRH3SMN1; SMN2KDM4ENPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145315-A1 | TARGETED PROTEIN DEGRADERS OF INDOLEAMINE 2,3-DIOXYGENASE 1 (IDO1) | NORTHWESTERN UNIVERSITY (US) | 2024-07-04 | — | — | WO | disclosed |