Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 5/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 5/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 3/20 | 0.31 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27505621 | 0.87 | GRIA1 (0.35) | GRIA1GRIA2GRIA3GRIA4ABCC8 | |
| SCHEMBL27551848 | 0.80 | GRIA1 (0.35) | GRIA1GRIA2GRIA3GRIA4ABCC8 | |
| SCHEMBL27540553 | 0.80 | GRIA1 (0.35) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7084826 | 0.79 | GRIA1 (0.34) | GRIA1GRIA2GRIA3GRIA4ABCC8 | |
| SCHEMBL27478466 | 0.78 | GRIA1 (0.40) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL27508021 | 0.78 | GRIA1 (0.37) | GRIA1GRIA2GRIA3GRIA4ABCC8 | |
| SCHEMBL27515613 | 0.77 | GRIA1 (0.36) | GRIA1GRIA2GRIA3GRIA4ABCC8 | |
| SCHEMBL27458108 | 0.77 | GRIA1 (0.32) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL27491409 | 0.77 | GRIA1 (0.38) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7077961 | 0.76 | GRIA1 (0.33) | GRIA1GRIA2GRIA3GRIA4ABCC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1158290-C | Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives, their preparation and use | ŵ��Ų�ڿ˹�˾ | 2004-07-21 | — | — | CN | claimed |
| CN-1208417-A | Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives, their preparation and use | NOVO NORDISK AS (DK) | 1999-02-17 | — | — | CN | claimed |
| CN-1158290-C | Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives, their preparation and use | ŵ��Ų�ڿ˹�˾ | 2004-07-21 | — | — | CN | disclosed |
| CN-1208417-A | Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives, their preparation and use | NOVO NORDISK AS (DK) | 1999-02-17 | — | — | CN | disclosed |