Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | PIM1 | P11309 | 1/20 | 0.57 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.57 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.55 |
| ▸ | CDC25B | P30305 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 5/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5758517 | 1.00 | MEN1 (0.59) | MEN1KMT2ANPC1PIM1PIM3 | |
| SCHEMBL5757608 | 1.00 | MEN1 (0.59) | MEN1KMT2ANPC1PIM1PIM3 | |
| SCHEMBL5758515 | 1.00 | MEN1 (0.59) | MEN1KMT2ANPC1PIM1PIM3 | |
| SCHEMBL5759953 | 0.99 | MEN1 (0.58) | MEN1KMT2ANPC1PIM1PIM3 | |
| SCHEMBL5759956 | 0.99 | MEN1 (0.58) | MEN1KMT2ANPC1PIM1PIM3 | |
| SCHEMBL6614894 | 0.99 | MEN1 (0.58) | MEN1KMT2ANPC1PIM1PIM3 | |
| SCHEMBL6614904 | 0.99 | MEN1 (0.58) | MEN1KMT2ANPC1PIM1PIM3 | |
| SCHEMBL6614897 | 0.99 | MEN1 (0.58) | MEN1KMT2ANPC1PIM1PIM3 | |
| SCHEMBL5759960 | 0.99 | MEN1 (0.58) | MEN1KMT2ANPC1PIM1PIM3 | |
| SCHEMBL7592721 | 0.95 | MEN1 (0.65) | MEN1KMT2ANPC1PIM1PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1162152-C | Therapeutic agent for diabetes | ��ʽ���縻��Ħ���������� | 2004-08-18 | — | — | CN | claimed |
| CN-1159305-C | Novel 2-(N-cyanoimino) thiazolidin-4-one derivatives | ��ʽ���縻��Ħ���������� | 2004-07-28 | — | — | CN | claimed |
| CN-1358096-A | Remedies for diabetes | FUJIMOTO BROTHERS CO LTD (JP) | 2002-07-10 | — | — | CN | claimed |
| CN-1333762-A | Novel 2-(N-cyanoimino) thiazolidin-4-one derivatives | FUJIMOTO BROTHERS CO LTD (JP) | 2002-01-30 | — | — | CN | claimed |
| CN-1162152-C | Therapeutic agent for diabetes | ��ʽ���縻��Ħ���������� | 2004-08-18 | — | — | CN | disclosed |
| CN-1159305-C | Novel 2-(N-cyanoimino) thiazolidin-4-one derivatives | ��ʽ���縻��Ħ���������� | 2004-07-28 | — | — | CN | disclosed |
| CN-1358096-A | Remedies for diabetes | FUJIMOTO BROTHERS CO LTD (JP) | 2002-07-10 | — | — | CN | disclosed |
| CN-1333762-A | Novel 2-(N-cyanoimino) thiazolidin-4-one derivatives | FUJIMOTO BROTHERS CO LTD (JP) | 2002-01-30 | — | — | CN | disclosed |