Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 0.61 |
| ▸ | EGFR | P00533 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | KDR | P35968 | 3/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MET | P08581 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6788335 | 0.89 | EGFR (0.60) | MAPK14EGFRKDRPDGFRAAURKA | |
| Hydrochloric Acid SCHEMBL6793325 | 0.88 | EGFR (0.59) | MAPK14EGFRKDRPDGFRAAURKA | |
| SCHEMBL6794349 | 0.78 | MAPK14 (0.81) | MAPK14EGFRKDRAURKAAURKB | |
| Hydrochloric Acid SCHEMBL27479012 | 0.78 | CLK1 (0.63) | MAPK14EGFRKDRPDGFRAHSD17B10 | |
| SCHEMBL27731208 | 0.78 | EGFR (0.65) | MAPK14EGFRHDAC1HDAC8HDAC6 | |
| SCHEMBL21358588 | 0.77 | PDGFRA (0.60) | EGFRKDRPDGFRAKITMET | |
| SCHEMBL21473619 | 0.74 | MAPK14 (0.81) | MAPK14EGFRKDRAURKAAURKB | |
| SCHEMBL4549026 | 0.74 | KDR (0.72) | KDRAURKAAURKBMET | |
| SCHEMBL27837488 | 0.74 | CYP1A2 (0.66) | MAPK14MEN1KMT2AHDAC1HDAC8 | |
| SCHEMBL2747364 | 0.73 | KDR (0.72) | KDRAURKAAURKBMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1158266-C | Chemical compounds | — | 2004-07-21 | — | — | CN | disclosed |
| CN-1321151-A | Chemical compounds | ASTRAZENECA AB (SE) | 2001-11-07 | — | — | CN | disclosed |