Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | TET3 | O43151 | 1/20 | 0.39 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 2/20 | 0.32 |
| ▸ | CPB1 | P15086 | 1/20 | 0.32 |
| ▸ | CPA3 | P15088 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL110197 | 0.81 | TDP1 (0.59) | TDP1SMN1; SMN2SLC22A6TET2FOLH1 | |
| SCHEMBL5221301 | 0.78 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6TET2FOLH1 | |
| SCHEMBL28497300 | 0.78 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6TET2FOLH1 | |
| SCHEMBL78919 | 0.78 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6TET2FOLH1 | |
| SCHEMBL5681439 | 0.78 | TDP1 (0.56) | TDP1SMN1; SMN2SLC22A6TET2FOLH1 | |
| SCHEMBL1472841 | 0.78 | TDP1 (0.56) | TDP1SMN1; SMN2SLC22A6TET2FOLH1 | |
| SCHEMBL3110310 | 0.75 | TDP1 (0.53) | TDP1SMN1; SMN2SLC22A6TET2FOLH1 | |
| SCHEMBL27653781 | 0.74 | TDP1 (0.40) | TDP1SMN1; SMN2SLC22A6TET2FOLH1 | |
| SCHEMBL16652346 | 0.71 | FFAR3 (0.38) | TDP1SMN1; SMN2SLC22A6TET2FOLH1 | |
| SCHEMBL10734056 | 0.71 | HDAC1 (0.44) | TDP1SMN1; SMN2SLC22A6FOLH1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1081672-A | carboxylic acid derivative and preparation method thereof | NIPPON SHINYAKU CO LTD (JP) | 1994-02-09 | — | — | CN | disclosed |