Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.76 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1160177 | 0.87 | PPARG (0.95) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL7650594 | 0.86 | PPARG (0.78) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| Atx08-001 SCHEMBL682052 | 0.86 | PPARG (1.00) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| Atx08-001 SCHEMBL29691565 | 0.86 | PPARG (1.00) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| Atx08-001 SCHEMBL29368164 | 0.86 | PPARG (1.00) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL1160394 | 0.86 | PPARG (0.70) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL7652251 | 0.85 | PPARG (0.69) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL6171221 | 0.85 | PPARG (0.69) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL6134141 | 0.85 | PPARG (0.68) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL6134137 | 0.85 | PPARG (0.68) | PPARGHDAC1HDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1135224-C | Benzimidazole derivatives | ����ҩƷ��ҵ��ʽ���� | 2004-01-21 | — | — | CN | disclosed |
| CN-1268123-A | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-09-27 | — | — | CN | disclosed |