Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6150412 | 0.83 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4632468 | 0.83 | EDNRA (0.66) | EDNRAEDNRB | |
| SCHEMBL4632467 | 0.83 | EDNRA (0.66) | EDNRAEDNRB | |
| SCHEMBL6151347 | 0.81 | EDNRA (0.72) | EDNRAEDNRB | |
| SCHEMBL7337364 | 0.80 | EDNRA (0.71) | EDNRAEDNRB | |
| SCHEMBL4630640 | 0.80 | EDNRA (0.71) | EDNRAEDNRB | |
| SCHEMBL4630649 | 0.80 | EDNRA (0.84) | EDNRAEDNRB | |
| SCHEMBL4631372 | 0.80 | EDNRA (0.84) | EDNRAEDNRB | |
| SCHEMBL4631370 | 0.80 | EDNRA (0.84) | EDNRAEDNRB | |
| SCHEMBL4630651 | 0.80 | EDNRA (0.84) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1636994-B | Process of preparing alkali metal salys of hydrophobic sulfonamides and alkali metal salt produced thereby | ENCYSIVE PHARMACEUTICALS INC | 2010-05-12 | — | — | CN | disclosed |
| CN-1636994-A | Process of preparing alkali metal salys of hydrophobic sulfonamides and alkali metal salt produced thereby | ENCYSIVE PHARMACEUTICALS INC (US) | 2005-07-13 | — | — | CN | disclosed |
| CN-1179961-C | Sulfonamides for the treatment of endothelin mediated diseases | ��ɪϣ����ҩ��˾ | 2004-12-15 | — | — | CN | disclosed |
| CN-1130355-C | Thienyl-, Furyl-, Pyrrolyl- and biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin | TEXAS BIOTECHNOLOGY CORP (US) | 2003-12-10 | — | — | CN | disclosed |
| CN-1253560-A | Sulfonamides for the treatment of endothelin mediated diseases | TEXA BIOTECHNOLOGY CORP (US) | 2000-05-17 | — | — | CN | disclosed |
| CN-1184470-A | Thienyl-, Furyl-, Pyrrolyl- and biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin | TEXAS BIOTECHNOLOGY CORP (US) | 1998-06-10 | — | — | CN | disclosed |