Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27468265 | 0.74 | CYP1A2 (0.36) | CYP1A2POLBGABRA5GABRB2 | |
| SCHEMBL27489810 | 0.70 | POLB (0.35) | CYP1A2POLBGABRA5GABRB2 | |
| SCHEMBL27519232 | 0.69 | POLB (0.34) | CYP1A2POLBGABRA5GABRB2 | |
| SCHEMBL15649927 | 0.69 | CYP1A2 (0.41) | CYP1A2POLBGABRA5GABRB2ALDH1A1 | |
| SCHEMBL27468729 | 0.68 | POLB (0.37) | CYP1A2POLBGABRA5GABRB2ALDH1A1 | |
| SCHEMBL27450939 | 0.68 | CYP1A2 (0.38) | CYP1A2POLBGABRA5GABRB2 | |
| SCHEMBL28255252 | 0.65 | — | — | |
| SCHEMBL8291577 | 0.65 | CYP1A2 (0.47) | CYP1A2POLBGABRA5GABRB2ALDH1A1 | |
| SCHEMBL27448587 | 0.64 | CYP1A2 (0.38) | CYP1A2POLBGABRA5GABRB2ALDH1A1 | |
| SCHEMBL9402309 | 0.60 | CYP2C19 (0.32) | CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1500773-A | Cyclic amino acids and derivatives thereof useful as pharmaceutical agents | ��ʲ | 2004-06-02 | — | — | CN | claimed |
| CN-1436075-A | Gabapentin analogues for sleep disorders | WARNER LAMBERT CO (US) | 2003-08-13 | — | — | CN | claimed |
| CN-1276784-A | Cyclic amino acids and their organisms as medicaments | WARNER LAMBERT CO (US) | 2000-12-13 | — | — | CN | claimed |
| CN-101283995-A | Different pharmaceutical uses alpha2delta ligands | WARNER LAMBERT CO (US) | 2008-10-15 | — | — | CN | disclosed |
| CN-1303059-C | Cyclic amino acids and derivatives thereof useful as pharmaceutical agents | WARNER LAMBERT CO (US) | 2007-03-07 | — | — | CN | disclosed |
| CN-1279900-C | Gabapentin analogues for sleep disorders | WARNER LAMBERT CO (US) | 2006-10-18 | — | — | CN | disclosed |
| CN-1726015-A | Alpha 2 delta ligands for different pharmaceutical uses | WARNER LAMBERT CO (US) | 2006-01-25 | — | — | CN | disclosed |
| CN-1500773-A | Cyclic amino acids and derivatives thereof useful as pharmaceutical agents | ��ʲ | 2004-06-02 | — | — | CN | disclosed |
| CN-1138755-C | Cyclic amino acids and derivatives thereof as pharmaceuticals | ��ʲ | 2004-02-18 | — | — | CN | disclosed |
| CN-1436075-A | Gabapentin analogues for sleep disorders | WARNER LAMBERT CO (US) | 2003-08-13 | — | — | CN | disclosed |
| CN-1276784-A | Cyclic amino acids and their organisms as medicaments | WARNER LAMBERT CO (US) | 2000-12-13 | — | — | CN | disclosed |