Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.53 |
| ▸ | CSF1R | P07333 | 5/20 | 0.52 |
| ▸ | KDR | P35968 | 3/20 | 0.52 |
| ▸ | KIT | P10721 | 2/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.52 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | FLT1 | P17948 | 1/20 | 0.51 |
| ▸ | FLT4 | P35916 | 1/20 | 0.51 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27483851 | 0.82 | PTGS1 (0.60) | PTGS1MEN1KMT2ATSHRRXFP1 | |
| SCHEMBL27468946 | 0.81 | PTGS1 (0.59) | PTGS1MEN1KMT2ATSHRRXFP1 | |
| SCHEMBL4978481 | 0.81 | RXFP1 (0.64) | MEN1KMT2ATSHRRXFP1CSF1R | |
| SCHEMBL4978213 | 0.75 | KDR (0.79) | MEN1KMT2ATSHRRXFP1CSF1R | |
| SCHEMBL27466657 | 0.75 | PTGS1 (0.64) | PTGS1MEN1KMT2ATSHRRXFP1 | |
| SCHEMBL27548630 | 0.74 | PTGS1 (0.63) | PTGS1MEN1KMT2ARXFP1CSF1R | |
| SCHEMBL4980974 | 0.74 | RXFP1 (0.79) | MEN1KMT2ATSHRRXFP1CSF1R | |
| SCHEMBL4031509 | 0.73 | PTGS1 (1.00) | PTGS1RXFP1MAPTGAAAHR | |
| SCHEMBL31424184 | 0.73 | PTGS1 (1.00) | PTGS1RXFP1MAPTGAAAHR | |
| SCHEMBL29392990 | 0.73 | PTGS1 (1.00) | PTGS1RXFP1MAPTGAAAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152014-C | N-aryl (thio) anthranilic acid amide derivatives, their prepn. and their use as VEGF receptor tyrosine kinase inhibitors | ��˹��ŵ�� | 2004-06-02 | — | — | CN | disclosed |
| CN-1331680-A | N-aryl (thio) anthranilic acid amide derivatives, their prepn. and their use as VEGF receptor tyrosine kinase inhibitors | NOVARTIS AG (CH) | 2002-01-16 | — | — | CN | disclosed |