Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 12/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27504953 | 0.91 | POLB (0.48) | PDE5APOLBALDH1A1HTTKDM4E | |
| SCHEMBL27504951 | 0.87 | PDE5A (0.50) | PDE5A | |
| SCHEMBL27447978 | 0.86 | PDE5A (0.51) | PDE5A | |
| Ammonia Solution, Strong SCHEMBL27466741 | 0.86 | PDE5A (0.60) | PDE5APOLBVCAM1MAPTALDH1A1 | |
| SCHEMBL27504655 | 0.85 | PDE5A (0.44) | PDE5A | |
| SCHEMBL27466245 | 0.83 | PDE5A (0.51) | PDE5AALDH1A1 | |
| SCHEMBL27468605 | 0.77 | PDE5A (0.51) | PDE5AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7914734 | 0.77 | PDE5A (0.60) | PDE5A | |
| SCHEMBL6597884 | 0.77 | PDE5A (0.80) | PDE5A | |
| SCHEMBL27548037 | 0.77 | PDE5A (0.55) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151136-C | Condensed pyridazine compound | ������������ʽ���� | 2004-05-26 | — | — | CN | disclosed |
| CN-1135210-A | Fused pyridazine compound | EISAI CO LTD (JP) | 1996-11-06 | — | — | CN | disclosed |