SCHEMBL27466909

SCHEMBL27466909

O=[PH](OCOS(=O)(=O)c1ccccc1C(F)(F)F)OCOS(=O)(=O)c1ccccc1C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
SLC22A12 Q96S37 13/20 0.39
RXFP1 Q9HBX9 1/20 0.37
HSD11B1 P28845 1/20 0.37
ALDH1A1 P00352 1/20 0.36
RAB9A P51151 1/20 0.36
CYP2C9 P11712 2/20 0.35
SLC22A6 Q4U2R8 2/20 0.35
SLC22A8 Q8TCC7 2/20 0.35
SLC22A11 Q9NSA0 2/20 0.35
MMP7 P09237 1/20 0.35
KAT6A Q92794 1/20 0.35
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8854529 0.88 MEN1 (0.41) MEN1KMT2ASLC22A12RXFP1HSD11B1
SCHEMBL8735599 0.88 MEN1 (0.32) MEN1KMT2AHSD11B1
SCHEMBL6115152 0.87 MEN1 (0.50) MEN1KMT2ASLC22A12RXFP1HSD11B1
SCHEMBL29449482 0.87 MEN1 (0.50) MEN1KMT2ASLC22A12RXFP1HSD11B1
SCHEMBL27448640 0.79 MEN1 (0.43) MEN1KMT2ASLC22A12RXFP1HSD11B1
SCHEMBL15000825 0.79 MEN1 (0.43) MEN1KMT2ASLC22A12RXFP1HSD11B1
SCHEMBL8762711 0.79 MEN1 (0.43) MEN1KMT2ASLC22A12RXFP1HSD11B1
SCHEMBL8732244 0.79 MEN1 (0.43) MEN1KMT2ASLC22A12RXFP1HSD11B1
SCHEMBL8854709 0.79 MEN1 (0.43) MEN1KMT2ASLC22A12RXFP1HSD11B1
SCHEMBL27449557 0.78 SLC22A12 (0.34) SLC22A12HSD11B1KAT6A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1133120-A Combination containing phosphine sulfonate ester herbicide and dichloro acetamide safety agent ROHM & HAAS (US) 1996-10-16 CN claimed