Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 16/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27467161 | 0.89 | KCNH2 (0.43) | GCKKCNH2RAB9A | |
| SCHEMBL27465177 | 0.87 | GCK (0.50) | GCKKCNH2 | |
| SCHEMBL27481289 | 0.87 | KCNH2 (0.42) | GCKKCNH2 | |
| SCHEMBL14278077 | 0.83 | GCK (0.63) | GCKKCNH2 | |
| SCHEMBL2646843 | 0.83 | GCK (0.63) | GCKKCNH2 | |
| SCHEMBL2647261 | 0.81 | GCK (0.49) | GCKKCNH2 | |
| SCHEMBL2646817 | 0.81 | KCNH2 (0.58) | GCKKCNH2RAB9A | |
| SCHEMBL2646116 | 0.80 | GCK (0.56) | GCKKCNH2 | |
| SCHEMBL2654411 | 0.78 | GCK (0.56) | GCKKCNH2 | |
| SCHEMBL2645543 | 0.77 | GCK (0.55) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151140-C | Glucokinase activators | - | 2004-05-26 | — | — | CN | disclosed |
| CN-1349519-A | Glucokinase activators | HOFFMANN LA ROCHE (CH) | 2002-05-15 | — | — | CN | disclosed |